Study identifies possible connection to autism development
in pregnant mothers that correlate with autism risk,” Lukens said. “I think the really important thing is to figure out what kind of things can be used to modulate the microbiome in the mother as effectively and safely as we can.”
While blocking IL-17a also might offer a way to prevent autism, Lukens said it comes with certain risks. “If you think about pregnancy, the body is basically accepting foreign tissue, which is a baby,” he said. “As a result, maintenance of embryonic health demands a complex balance of immune regulation, so people tend to shy away from manipulating the immune system during pregnancy.”
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He suggested there are plenty of other molecules to explore, as IL-17a is just a tiny part of a much bigger picture.
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